Epigenetics: Tools, Diagnostics, Drugs and World Market

Product Code TKD00013
Publication Date August 2010
Publisher Takeda Pacific
Product Type Report
Pages 150
ISBN Number not applicable

Epigenetics: Tools, Diagnostics, Drugs and World Market

This broad and high-level report examines the emerging epigenetics market.  This world market includes important biomedical product areas that will have a powerful impact on healthcare delivery and personalized medicine. This business report analyzes key market segments such life science research tools, diagnostics and therapeutics.

Many people already know about DNA, genes and the human genome.  The DNA code defines the structure of who we are, our potential health and our characteristics that we pass on to our children.  Epigenetics refers to the second code of life and links environmental impacts to a person’s health. Epigenetic mechanisms signal how and when genes are activated or silenced.

This research study discusses the market for life science tools and technologies that support epigenetics R&D.  The report discusses important technologies, equipment and consumables including microarray, next-generation sequencing, PCR and other platforms.  Topics such as microRNA and human stem cells are lightly covered.

The report covers subjects including important epigenetic factors including DNA methylation, histone modifications and others.  The study discusses epigenetic biomarkers, commercial diagnostics and therapeutics that will foster personalized medicine.  The study highlights new epigenetic diagnostics. This research examines the current epigenetic therapeutics on the market and drugs in the clinical pipeline.  The report highlights major government grant initiatives such as the NIH’s ‘Roadmap Epigenomics Program’ initiatives, the EU’s ‘Epigenetic Network of Excellence’ and others.

This study discusses important epigenetics topics and provides the reader with key findings.  The data estimates that the worldwide epigenetics market value will reach multi-billions of dollars in 2010, with a strong double-digit growth rate. This report reviews the activities of 35 companies.  The study uses 39 figures and tables to illustrate the findings.  This study includes many valuable tables that help the reader scan the details of major trends, market segmentation, forecast, M&As, partnerships, grant funding, patents and so on.

This must-have report would benefit people with job titles including CEO, VPs, Director of Business Development, Research Directors, Entrepreneurs, Venture Capitalists, Investment Planners, Research Scientists, Consultants or Industry Analysts.

Contents

1. The Epigenetics Market Landscape

Epigenetics for R&D, Diagnostics & Therapeutics

    Brief History

    Understanding Epigenetic Mechanisms

    Epigenetics, Key Diseases and Demographics

    Tools & Technologies for Epigenetic R&D

    Epigenetic Diagnostic Tests

    Epigenetic-Based Therapeutics

Key Business Applications

    Academic Research Applications

    Diagnostic Applications

    Therapeutic Applications

2. Major Alliances, M&As and IP

Major Alliances and M&As In Epigenetics

    Definitions of Deal Types

    Summary of Major Epigenetics Alliances and M&As

    Alliance and M&A Data Tables

Patents, Business Development and Challenges

    Highlights of Companies That Own IP Involving Epigenetic Techs.

    Valuations of Epigenetic Technologies and Products

    Business Development Challenges

    Patent Challenges

3. Epigenetics Market Forecast

Epigenetics Product Market Size, 2008~2013

Epigenetic Market by Product Segments

    Epigenetic R&D Tools and Technologies Segments

    Epigenetic Diagnostics Segments

    Epigenetic Therapeutics Segments

    WW Epigenetic Market By Vendor Product Shares, 2008 & 2013

Market by Major Diseases

    Cancer Segment

    Neuro-psychological (CNS) Segment

    Infectious Disease Segment

    Respiratory Segment

    Reproductive Disease Segment

    The ‘Others’ Segment

Epigenetic Market by R&D Developer Segments

    Academic/Gov. Basic Life Science R&D Sub-segments

    Diagnostics Developer Segments

    Pharma/ Biotech Rx/Tx Developer Segments

Epigenetics Market by WW Regions

    North America

    Europe

    Japan/ Asia Pacific

    ROW

4. Selected Companies Working in Epigenetics

454 Life Sciences (Roche)

Abcam plc

Active Motif, Inc.

Affymetrix, Inc.

Agilent Technologies, Inc., BAM/LS

Applied Biosystems Group

AVIVA Systems Biology

BioServe

Cogenics (Clinical Data)

DNASTAR, Inc.

Epigenomics AG

Epigentek, Inc.

Epiontis GmbH

Fluidigm Corporation

GATC Biotech AG

GeneGo, Inc.

Genomatix Software GmbH

GenomeQuest, Inc.

Genpathway, Inc.

Human Genetic Signatures Pty. Ltd.

Illumina, Inc.

Invitrogen

Methylgene, Inc.

MGI Pharma, Inc. (subsidiary of Eisai)

Millipore

OncoMethylome Sciences SA

Orion Genomics LLC

Qiagen  N.V.

Regulus Therapeutics LLC

Roche Nimblegen

Rubicon Genomics, Inc.

Sequenom

SeqWright, Inc.

Sigma-Aldrich Co.

Zymo Research Corp.

5. Findings and Conclusions

Epigenetics Market Future Direction

    Analytical Tools for Epigenetic R&D

        Commercial DNA Microarrays, ChIP on Chip and Methylation

       High-Throughput Sequencing and ChIP-Seq.

       Other Front Runner Technologies

   Consumables & Reagent Kits

   Commercial Diagnostic/ Test Services

   Therapeutics Involving Epigenetics

Epigenetics Market Drivers and Restraints

   The US NIH Roadmap Epigenomics Program Initiatives

   The European Union Epigenetics Initiative

   M&A Deals Have Helped Epigenetic Product Companies

   FDA Approved Epigenetic Diagnostics Have Reached the Market

   FDA Approved Epigenetic Therapeutics Have Reached the Market

Potential Business Opportunities

   Opportunities for American and European Companies

      Epigenetic Diagnostics

      Consider Other World Regions for Cost Savings or New Customers

      Market into Asia for Business Opportunities

   Business Opportunities for Asian Companies

6. Appendix

Epigenetics Glossary

Company Contacts

Selected Grant Recipients for Epigenetics or Epigenomic Projects

About Takeda Pacific

About the Authors

 

List of Tables

Table 1. Epigenetics Disease Demographics

Table 2. Summary of Major Alliances and M&As, 2005 to Oct.- 2008

Table 3. Alliances and M&As Jan. to Oct. 2008

Table 4. Major Alliances and M&As - 2007

Table 5. Major Alliances and M&As - 2006

Table 6. Major Alliances and M&As - 2005

Table 7. Epigenetics Related US Patents Issued to Orgs., 2007 to Oct.- 2008

Table 8. Valuations of Major M&As Involving Epigenetics.

Table 9. Total WW Epigenetic Product Market Revenues, 2008-2013

Table 10. WW Epigenetic Market By Vendor Products $M

Table 11. Epigenetic R&D Tools & Technologies Sub-segments $M

Table 12. Epigenetic Diagnostics Sub-segments $M

Table 13. Epigenetic Therapeutics Sub-segments $M

Table 14. WW Epigenetic Market By Vendor Product Shares, 2008 & 2013

Table 15. WW Epigenetic Market By Leading Diseases $M

Table 16. Major Cancer Types Targeted in R&D and Shares

Table 17. WW Epigenetic Market By Developer Segments $M

Table 18. Academic/Gov. Basic Life Science R&D $M

Table 19. Diagnostics Developers

Table 20. Pharma/ Biotech Rx/Tx Developers

Table 21. WW Epigenetic Market By Regions $M

Table 22. High-Density Whole Genome Microarrays for Epigenetics

Table 23. High-Throughput DNA Sequencing For Epigenetics

Table 24. Other Technologies for Epigenetics

Table 25. Epigenetic Diagnostics Development Pipeline

Table 26. Therapeutics in Clinical Pipeline Involving Epigenetics

Table 27. NIH Roadmap Epigenomics Program Initiatives

Table 28. Glossary of Epigenetic Terms

Table 29. List of Company Contacts

Table 30. Selected NIH Grant Recipients and Epigenomic Projects

 

 

List of Figures

Figure 1. The Epigenetic Market Ecosystem

Figure 2. Highlights of Epigenetic Mechanisms

Figure 3. Growing Number of PubMed Articles About Epigenetics

Figure 4. Total WW Epigenetic Product Market Revenues, 2008-2013

Figure 5. WW Epigenetic Market By Vendor Products $M

Figure 6. WW Epigenetic Market By Product Market Shares, 2008 & 2013

Figure 7. WW Epigenetic Market By Major Diseases $M

Figure 8. WW Epigenetic Market By Developer Segments $M

Figure 9. WW Epigenetic Market By Regions $M